4CPH

trans-divalent streptavidin with love-hate ligand 4

Summary for 4CPH

Entry DOI	10.2210/pdb4cph/pdb
Related	4CPE 4CPF 4CPI
Descriptor	STREPTAVIDIN, 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide, ... (4 entities in total)
Functional Keywords	biotin binding protein, avidin, biotin, strain, biotinylated, steric clash, strained, hindered, force, ligand series, affinity
Biological source	STREPTOMYCES AVIDINII More
Total number of polymer chains	4
Total formula weight	56182.61
Authors	Fairhead, M.,Shen, D.,Chan, L.K.M.,Lowe, E.D.,Donohoe, T.J.,Howarth, M. (deposition date: 2014-02-06, release date: 2014-08-06, Last modification date: 2023-12-20)
Primary citation	Fairhead, M.,Shen, D.,Chan, L.K.M.,Lowe, E.D.,Donohoe, T.J.,Howarth, M. Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22:5476-, 2014 Cited by PubMed: 25128469 DOI: 10.1016/J.BMC.2014.07.029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation