8JV8
Cryo-EM structure of the panda P2X7 receptor in complex with PPNDS
Summary for 8JV8
Entry DOI | 10.2210/pdb8jv8/pdb |
EMDB information | 36671 |
Descriptor | P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, ... (4 entities in total) |
Functional Keywords | channel, transport protein |
Biological source | Ailuropoda melanoleuca (giant panda) |
Total number of polymer chains | 3 |
Total formula weight | 119295.25 |
Authors | Sheng, D.,Hattori, M. (deposition date: 2023-06-27, release date: 2023-11-29, Last modification date: 2024-04-24) |
Primary citation | Sheng, D.,Yue, C.,Jin, F.,Wang, Y.,Ichikawa, M.,Yu, Y.,Guo, C.R.,Hattori, M. Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists Elife, 2023 Cited by DOI: 10.7554/eLife.92829.1PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.34 Å) |
Structure validation
Download full validation report