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4CPE

Wild-type streptavidin in complex with love-hate ligand 1 (LH1)

Summary for 4CPE
Entry DOI10.2210/pdb4cpe/pdb
Related4CPF 4CPH 4CPI
DescriptorSTREPTAVIDIN, (3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N-{2-[(2,6- diphenylphenyl)formamido]ethyl}pentanamide (3 entities in total)
Functional Keywordsbiotin-binding protein, avidin, biotin, strain, biotinylated, steric clash, strained, hindered, force, ligand series, affinity
Biological sourceSTREPTOMYCES AVIDINII
Total number of polymer chains2
Total formula weight27648.06
Authors
Fairhead, M.,Shen, D.,Chan, L.K.M.,Lowe, E.D.,Donohoe, T.J.,Howarth, M. (deposition date: 2014-02-06, release date: 2014-08-06, Last modification date: 2023-12-20)
Primary citationFairhead, M.,Shen, D.,Chan, L.K.M.,Lowe, E.D.,Donohoe, T.J.,Howarth, M.
Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction.
Bioorg.Med.Chem., 22:5476-, 2014
Cited by
PubMed: 25128469
DOI: 10.1016/J.BMC.2014.07.029
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.06 Å)
Structure validation

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