7C7Q

Cryo-EM structure of the baclofen/BHFF-bound human GABA(B) receptor in active state

Summary for 7C7Q

• Entry DOI: 10.2210/pdb7c7q/pdb
• EMDB information: 30300
• Descriptor: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: gabab, cryo-em, gpcr, active, pam, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 188208.78

Authors

Mao, C.,Shen, C.,Li, C.,Shen, D.,Xu, C.,Zhang, S.,Zhou, R.,Shen, Q.,Chen, L.,Jiang, Z.,Liu, J.,Zhang, Y. (deposition date: 2020-05-26, release date: 2020-07-01, Last modification date: 2020-07-29)

• Primary citation: Mao, C.,Shen, C.,Li, C.,Shen, D.D.,Xu, C.,Zhang, S.,Zhou, R.,Shen, Q.,Chen, L.N.,Jiang, Z.,Liu, J.,Zhang, Y.; Cryo-EM structures of inactive and active GABABreceptor.; Cell Res., 30:564-573, 2020; PubMed: 32494023; DOI: 10.1038/s41422-020-0350-5

Experimental method

ELECTRON MICROSCOPY (3 Å)