Author results

3J5M
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CRYO-EM STRUCTURE OF THE BG505 SOSIP.664 HIV-1 ENV TRIMER WITH 3 PGV04 FABS
分子名称:BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 light chain, ...
著者Lyumkis, D., Julien, J.-P., Wilson, I.A., Ward, A.B.
登録日2013-10-26
公開日2013-11-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
4C3G
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CRYO-EM STRUCTURE OF ACTIVATED AND OLIGOMERIC RESTRICTION ENDONUCLEASE SGRAI
分子名称:SGRAIR RESTRICTION ENZYME, 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3'
著者Lyumkis, D., Talley, H., Stewart, A., Shah, S., Park, C.K., Tama, F., Potter, C.S., Carragher, B., Horton, N.C.
登録日2013-08-23
公開日2013-09-11
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.
Structure, 21, 2013
5TQW
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CRYOEM RECONSTRUCTION OF HUMAN IKK1, OPEN CONFORMATION 1
分子名称:Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D., Ghosh, G., Polley, S., Biswath, T., Huang, D., Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
5TQX
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CRYOEM RECONSTRUCTION OF HUMAN IKK1, INTERMEDIATE CONFORMATION 2
分子名称:Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D., Ghosh, G., Polley, S., Biswath, T., Huang, D., Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
5TQY
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CRYOEM RECONSTRUCTION OF HUMAN IKK1, CLOSED CONFORMATION 3
分子名称:Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D., Ghosh, G., Polley, S., Biswath, T., Huang, D., Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
5U1C
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STRUCTURE OF TETRAMERIC HIV-1 STRAND TRANSFER COMPLEX INTASOME
分子名称:HIV-1 Integrase, Sso7d chimera, DNA (11-MER), ...
著者Lyumkis, D., Passos, D.
登録日2016-11-28
公開日2017-01-11
最終更新日2017-09-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.
Science, 355, 2017
5EBZ
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CRYSTAL STRUCTURE OF HUMAN IKK1
分子名称:Inhibitor of nuclear factor kappa-B kinase subunit alpha, 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide, [(2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-4,6-bis(oxidanyl)-5-sulfooxy-oxan-3-yl] hydrogen sulfate, ...
著者Polley, S., Passos, D., Huang, D., Biswas, T., Verma, I., Lyumkis, D., Ghosh, G.
登録日2015-10-20
公開日2016-11-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
4NCO
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CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH THE BROADLY NEUTRALIZING FAB PGT122
分子名称:BG505 SOSIP gp120, BG505 SOSIP gp41, PGT122 light chain, ...
著者Julien, J.-P., Stanfield, R.L., Lyumkis, D., Ward, A.B., Wilson, I.A.
登録日2013-10-24
公開日2013-11-13
最終更新日2014-01-15
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
6ME0
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STRUCTURE OF A GROUP II INTRON RETROELEMENT PRIOR TO DNA INTEGRATION
分子名称:T.el4h RNA, Sense Target DNA, Maturase reverse transcriptase, ...
著者Haack, D., Yan, X., Zhang, C., Hingey, J., Lyumkis, D., Baker, T.S., Toor, N.
登録日2018-09-05
公開日2019-08-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA.
Cell, 178, 2019
6MEC
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STRUCTURE OF A GROUP II INTRON RETROELEMENT AFTER DNA INTEGRATION
分子名称:T.el4h RNA, Sense Target DNA, Maturase reverse transcriptase, ...
著者Haack, D., Yan, X., Zhang, C., Hingey, J., Lyumkis, D., Baker, T.S., Toor, N.
登録日2018-09-06
公開日2019-08-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA.
Cell, 178, 2019
3JBS
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EL6 PROTEIN FROM YEAST 60S RIBOSOMAL SUBUNIT
分子名称:eL6
著者Passos, D.O., Lyumkis, D.
登録日2015-10-13
公開日2015-10-28
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Single-particle cryoEM analysis at near-atomic resolution from several thousand asymmetric subunits.
J.Struct.Biol., 192, 2015
6E9D
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SUB-2 ANGSTROM EWALD CURVATURE-CORRECTED SINGLE-PARTICLE CRYO-EM RECONSTRUCTION OF AAV-2 L336C
分子名称:Capsid protein VP1
著者Tan, Y.Z., Aiyer, S., Mietzsch, M., Hull, J.A., McKenna, R., Baker, T.S., Agbandje-McKenna, M., Lyumkis, D.
登録日2018-07-31
公開日2018-08-15
最終更新日2018-09-19
実験手法ELECTRON MICROSCOPY (1.86 Å)
主引用文献Sub-2 angstrom Ewald curvature corrected structure of an AAV2 capsid variant.
Nat Commun, 9, 2018
6E9E
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ESCAS13D-CRRNA BINARY COMPLEX
分子名称:crRNA (52-MER), EsCas13d, MAGNESIUM ION
著者Zhang, C., Lyumkis, D.
登録日2018-08-01
公開日2018-10-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell, 175, 2018
6E9F
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ESCAS13D-CRRNA-TARGET RNA TERNARY COMPLEX
分子名称:EsCas13d, crRNA (52-MER), RNA (27-MER), ...
著者Zhang, C., Lyumkis, D.
登録日2018-08-01
公開日2018-10-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.
Cell, 175, 2018
3JCA
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CORE MODEL OF THE MOUSE MAMMARY TUMOR VIRUS INTASOME
分子名称:Integrase, 5'-D(*AP*AP*TP*GP*CP*CP*GP*CP*AP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*CP*TP*G)-3', 5'-D(*CP*AP*GP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*TP*GP*CP*GP*GP*CP*A)-3', ...
著者Lyumkis, D.L., Ballandras-Colas, A., Brown, M., Cook, N.J., Dewdney, T.G., Demeler, B., Cherepanov, P., Engelman, A.N.
登録日2015-11-24
公開日2016-02-17
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
5ACO
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CRYO-EM STRUCTURE OF PGT128 FAB IN COMPLEX WITH BG505 SOSIP.664 ENV TRIMER
分子名称:HIV-1 ENVELOPE GLYCOPROTEIN, PGT128 FAB, N-ACETYL-D-GLUCOSAMINE, ...
著者Lee, J.H., Ward, A.B.
登録日2015-08-17
公開日2015-09-30
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.
Structure, 23, 2015
5CZ1
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF MMTV INTEGRASE
分子名称:integrase
著者Cook, N., Ballandras-Colas, A., Engelman, A., Cherepanov, P.
登録日2015-07-31
公開日2016-02-17
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
5CZ2
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CRYSTAL STRUCTURE OF A TWO-DOMAIN FRAGMENT OF MMTV INTEGRASE
分子名称:Pol polyprotein, MAGNESIUM ION, ZINC ION
著者Cook, N., Ballandras-Colas, A., Engelman, A., Cherepanov, P.
登録日2015-07-31
公開日2016-02-17
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
5D7U
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF MMTV INTEGRASE
分子名称:Pr160, ISOPROPYL ALCOHOL
著者Cook, N.J., Pye, V.E., Ballandras-Colas, A., Engelman, A., Cherepanov, P.
登録日2015-08-14
公開日2016-02-17
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
5VN3
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CRYO-EM MODEL OF B41 SOSIP.664 IN COMPLEX WITH SOLUBLE CD4 (D1-D2) AND FRAGMENT ANTIGEN BINDING VARIABLE DOMAIN OF 17B
分子名称:17b Fab light chain, Envelope glycoprotein gp160, T-cell surface glycoprotein CD4, ...
著者Ozorowski, G., Pallesen, J., Ward, A.B.
登録日2017-04-28
公開日2017-07-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5VN8
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CRYO-EM MODEL OF B41 SOSIP.664 IN COMPLEX WITH FRAGMENT ANTIGEN BINDING VARIABLE DOMAIN OF B12
分子名称:Envelope glycoprotein gp160, b12 Fab heavy chain, b12 Fab light chain, ...
著者Ozorowski, G., Pallesen, J., Ward, A.B., Cottrell, C.A.
登録日2017-04-28
公開日2017-07-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017