8SY6

E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site

Summary for 8SY6

• Entry DOI: 10.2210/pdb8sy6/pdb
• EMDB information: 40863
• Descriptor: Non-template single stranded DNA, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, ... (11 entities in total)
• Functional Keywords: complex, unnatural base pairs, synthetic biology, transcription, transcription-dna-rna complex, transcription/dna/rna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 8
• Total formula weight: 410618.06

Authors

Shan, Z.,Lyumkis, D.,Oh, J.,Wang, D. (deposition date: 2023-05-24, release date: 2023-12-27)

• Primary citation: Oh, J.,Shan, Z.,Hoshika, S.,Xu, J.,Chong, J.,Benner, S.A.,Lyumkis, D.,Wang, D.; A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.; Nat Commun, 14:8219-8219, 2023; PubMed: 38086811; DOI: 10.1038/s41467-023-43735-9

Experimental method

ELECTRON MICROSCOPY (3.28 Å)