7SJX

Cryo-EM Structure of the PR-RT components of the HIV-1 Pol Polyprotein

This is a non-PDB format compatible entry.

Summary for 7SJX

• Entry DOI: 10.2210/pdb7sjx/pdb
• EMDB information: 25165
• Descriptor: Gag-Pol polyprotein (1 entity in total)
• Functional Keywords: hiv-1, reverse transcriptase, protease, viral protein, enzyme
• Biological source: Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 238579.73

Authors

Lyumkis, D.,Passos, D.,Arnold, E.,Harrison, J.J.E.K.,Ruiz, F.X. (deposition date: 2021-10-19, release date: 2022-07-27, Last modification date: 2023-08-16)

• Primary citation: Harrison, J.J.E.K.,Passos, D.O.,Bruhn, J.F.,Bauman, J.D.,Tuberty, L.,DeStefano, J.J.,Ruiz, F.X.,Lyumkis, D.,Arnold, E.; Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation.; Sci Adv, 8:eabn9874-eabn9874, 2022; PubMed: 35857464; DOI: 10.1126/sciadv.abn9874

Experimental method

ELECTRON MICROSCOPY (8.2 Å)