3J5M

Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs

Summary for 3J5M

Related4NCO
EMDB information5779
DescriptorBG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 light chain, ... (4 entities in total)
Functional Keywordshiv-1 trimeric spike, gp140, sosip, broadly neutralizing antibody, pgv04, env, envelope glycoprotein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
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Total number of polymer chains12
Total molecular weight318913.28
Authors
Lyumkis, D.,Julien, J.-P.,Wilson, I.A.,Ward, A.B. (deposition date: 2013-10-26, release date: 2013-11-13, Last modification date: 2018-07-18)
Primary citation
Lyumkis, D.,Julien, J.P.,de Val, N.,Cupo, A.,Potter, C.S.,Klasse, P.J.,Burton, D.R.,Sanders, R.W.,Moore, J.P.,Carragher, B.,Wilson, I.A.,Ward, A.B.
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342:1484-1490, 2013
PubMed: 24179160 (PDB entries with the same primary citation)
DOI: 10.1126/science.1245627
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers92.2%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
167518
PDB entries from 2020-08-12