3J5M
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, I | BG505 SOSIP gp120 | polymer | 475 | 53121.1 | 3 | UniProt (Q2N0S6) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | B, F, J | BG505 SOSIP gp41 | polymer | 64 | 5464.7 | 3 | Human immunodeficiency virus 1 | ||
3 | C, G, K | PGV04 light chain | polymer | 208 | 23073.8 | 3 | Homo sapiens (human) | ||
4 | D, H, L | PGV04 heavy chain | polymer | 228 | 24644.8 | 3 | Homo sapiens (human) |
Sequence modifications
A, E, I: 31 - 507 (UniProt: Q2N0S6)
PDB | External Database | Details |
---|---|---|
Asn 332 | Thr 330 | ENGINEERED MUTATION |
Cys 501 | Ala 498 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 318913.3 | |
All* | Total formula weight | 318913.3 |