4NCO
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
Summary for 4NCO
Entry DOI | 10.2210/pdb4nco/pdb |
Related | 3J5M 4JY4 4JY5 4JY6 |
Related PRD ID | PRD_900111 |
Descriptor | BG505 SOSIP gp120, BG505 SOSIP gp41, PGT122 light chain, ... (8 entities in total) |
Functional Keywords | type-1 membrane fusion glycoprotein trimer, hiv-1 envelope, gp120, gp41, membrane fusion, viral entry, cd4, ccr5/cxcr4, broadly neutralizing antibodies, viral surface, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 350934.77 |
Authors | Julien, J.-P.,Stanfield, R.L.,Lyumkis, D.,Ward, A.B.,Wilson, I.A. (deposition date: 2013-10-24, release date: 2013-11-13, Last modification date: 2023-09-20) |
Primary citation | Julien, J.P.,Cupo, A.,Sok, D.,Stanfield, R.L.,Lyumkis, D.,Deller, M.C.,Klasse, P.J.,Burton, D.R.,Sanders, R.W.,Moore, J.P.,Ward, A.B.,Wilson, I.A. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science, 342:1477-1483, 2013 Cited by PubMed: 24179159DOI: 10.1126/science.1245625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.7 Å) |
Structure validation
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