5TQY
CryoEM reconstruction of human IKK1, closed conformation 3
Summary for 5TQY
| Entry DOI | 10.2210/pdb5tqy/pdb |
| Related | 5TQW 5TQX |
| EMDB information | 8436 8437 8438 8439 |
| Descriptor | Inhibitor of nuclear factor kappa-B kinase subunit alpha (1 entity in total) |
| Functional Keywords | kinase, conserved helix-loop-helix, transcription, oncogene, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 150293.89 |
| Authors | Lyumkis, D.,Ghosh, G.,Polley, S.,Biswath, T.,Huang, D.,Passos, D.O. (deposition date: 2016-10-24, release date: 2016-11-09, Last modification date: 2024-03-13) |
| Primary citation | Polley, S.,Passos, D.O.,Huang, D.B.,Mulero, M.C.,Mazumder, A.,Biswas, T.,Verma, I.M.,Lyumkis, D.,Ghosh, G. Structural Basis for the Activation of IKK1/ alpha. Cell Rep, 17:1907-1914, 2016 Cited by PubMed: 27851956DOI: 10.1016/j.celrep.2016.10.067 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.2 Å) |
Structure validation
Download full validation report
