4C3G

cryo-EM structure of activated and oligomeric restriction endonuclease SgrAI

Summary for 4C3G

• Entry DOI: 10.2210/pdb4c3g/pdb
• EMDB information: 2441
• Descriptor: SGRAIR RESTRICTION ENZYME, 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3' (3 entities in total)
• Functional Keywords: hydrolase, restriction endonuclease, allostery, dna cleavage, parasite-host interaction
• Biological source: STREPTOMYCES GRISEUS; More
• Total number of polymer chains: 6
• Total formula weight: 100309.57

Authors

Lyumkis, D.,Talley, H.,Stewart, A.,Shah, S.,Park, C.K.,Tama, F.,Potter, C.S.,Carragher, B.,Horton, N.C. (deposition date: 2013-08-23, release date: 2013-09-11, Last modification date: 2017-08-23)

• Primary citation: Lyumkis, D.,Talley, H.,Stewart, A.,Shah, S.,Park, C.K.,Tama, F.,Potter, C.S.,Carragher, B.,Horton, N.C.; Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.; Structure, 21:1848-, 2013; PubMed: 24055317; DOI: 10.1016/J.STR.2013.08.012

Experimental method

ELECTRON MICROSCOPY (8.6 Å)