7C7S
 
 | | Cryo-EM structure of the CGP54626-bound human GABA(B) receptor in inactive state. | | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Mao, C, Shen, C, Li, C, Shen, D, Xu, C, Zhang, S, Zhou, R, Shen, Q, Chen, L, Jiang, Z, Liu, J, Zhang, Y. | | 登録日 | 2020-05-26 | | 公開日 | 2020-07-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of inactive and active GABABreceptor.
Cell Res., 30, 2020
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6V06
 | | Crystal structure of Beta-2 glycoprotein I purified from plasma (pB2GPI) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-glycoprotein 1, ... | | 著者 | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
J.Biol.Chem., 295, 2020
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6V09
 | | Crystal structure of human recombinant Beta-2 glycoprotein I short tag (ST-B2GPI) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ... | | 著者 | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
J.Biol.Chem., 295, 2020
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6V08
 | | Crystal structure of human recombinant Beta-2 glycoprotein I (hrB2GPI) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ... | | 著者 | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | | 登録日 | 2019-11-18 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.
J.Biol.Chem., 295, 2020
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6VWU
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6XZ6
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6ILK
 | | Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 7.4 | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | | 登録日 | 2018-10-18 | | 公開日 | 2019-05-15 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
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6ILJ
 | | Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5 | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | | 登録日 | 2018-10-18 | | 公開日 | 2019-05-15 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
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6H03
 | | OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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6H04
 | | Closed conformation of the Membrane Attack Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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6EYK
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV355 | | 分子名称: | (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R},3~{S})-3-methyl-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxy-cyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | E-selectin lectin with different glycomimetic ligands
To Be Published
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6EYJ
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV354 | | 分子名称: | (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[(1~{R},2~{R})-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxycyclohexyl]oxy-oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | E-selectin lectin with different glycomimetic ligands
To Be Published
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6EYI
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669 | | 分子名称: | (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | | 登録日 | 2017-11-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | E-selectin lectin with different glycomimetic ligands
To Be Published
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6ATG
 | | Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis | | 分子名称: | Complement regulator-acquiring surface protein 2 (CRASP-2), HCG40889, isoform CRA_b, ... | | 著者 | Liu, A, Yan, H, Wu, Y, Li, Y, Liu, J. | | 登録日 | 2017-08-29 | | 公開日 | 2018-09-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
To Be Published
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5NBQ
 | | The structure of the tripartite complex between OspE, the C-terminal domains of factor H and C3dg | | 分子名称: | Complement C3, Complement factor H, Outer surface protein E, ... | | 著者 | Kolodziejczyk, R, Mikula, K.M, Kotila, T.M, Postis, V.L.G, Sakari, J.T, Meri, T. | | 登録日 | 2017-03-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi.
PLoS ONE, 12, 2017
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5UBM
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5WTB
 | | Complex Structure of Staphylococcus aureus SdrE with human complement factor H | | 分子名称: | Peptide from Complement factor H, Serine-aspartate repeat-containing protein E | | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | | 登録日 | 2016-12-10 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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5O35
 | | Structure of complement proteins complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Complement factor H,Complement factor H | | 著者 | Xue, X, Wu, J, Forneris, F, Gros, P. | | 登録日 | 2017-05-23 | | 公開日 | 2017-06-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
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5O32
 | | The structure of complement complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Xue, X, Wu, J, Forneris, F, Gros, P. | | 登録日 | 2017-05-23 | | 公開日 | 2017-06-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4.206209 Å) | | 主引用文献 | Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
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5JPM
 | | Structure of the complex of human complement C4 with MASP-2 rebuilt using iMDFF | | 分子名称: | Complement C4-A, Mannan-binding lectin serine protease 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Croll, T.I, Andersen, G.R. | | 登録日 | 2016-05-03 | | 公開日 | 2016-08-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4.
Acta Crystallogr D Struct Biol, 72, 2016
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5HZP
 | | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein. | | 分子名称: | C4b-binding protein alpha chain, M protein, serotype 49, ... | | 著者 | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | | 登録日 | 2016-02-02 | | 公開日 | 2016-07-20 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
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5HYP
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5HYT
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5HYU
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5I0Q
 | | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein | | 分子名称: | C4b-binding protein alpha chain, M protein, serotype 2.1 | | 著者 | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | | 登録日 | 2016-02-04 | | 公開日 | 2016-07-20 | | 最終更新日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | | 主引用文献 | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
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