5HZP
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein.
Summary for 5HZP
Entry DOI | 10.2210/pdb5hzp/pdb |
Related | 5HYP 5HYT 5HYU 5I0Q |
Descriptor | M protein, serotype 49, C4b-binding protein alpha chain, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | m protein, compliment, streptococcus pyogenes, hypervariable antigen, immune system |
Biological source | Streptococcus pyogenes serotype M49 More |
Total number of polymer chains | 4 |
Total formula weight | 50215.11 |
Authors | Buffalo, C.Z.,Bahn-Suh, A.J.,Ghosh, P. (deposition date: 2016-02-02, release date: 2016-07-20, Last modification date: 2019-12-11) |
Primary citation | Buffalo, C.Z.,Bahn-Suh, A.J.,Hirakis, S.P.,Biswas, T.,Amaro, R.E.,Nizet, V.,Ghosh, P. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1:16155-16155, 2016 Cited by PubMed: 27595425DOI: 10.1038/nmicrobiol.2016.155 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.74 Å) |
Structure validation
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