5HYP

Structure of human C4b-binding protein alpha cain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M28 protein

Summary for 5HYP

• Entry DOI: 10.2210/pdb5hyp/pdb
• Related: 5HYT 5HYU 5HZP 5I0Q
• Descriptor: C4b-binding protein alpha chain, M28 protein (2 entities in total)
• Functional Keywords: m protein, complement, streptococcus pyogenes, hypervariable antigen, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 26357.32

Authors

Buffalo, C.Z.,Bahn-Suh, A.J.,Ghosh, P. (deposition date: 2016-02-01, release date: 2016-07-20, Last modification date: 2023-09-27)

• Primary citation: Buffalo, C.Z.,Bahn-Suh, A.J.,Hirakis, S.P.,Biswas, T.,Amaro, R.E.,Nizet, V.,Ghosh, P.; Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.; Nat Microbiol, 1:16155-16155, 2016; PubMed: 27595425; DOI: 10.1038/nmicrobiol.2016.155

Experimental method

X-RAY DIFFRACTION (3.024 Å)