6EYI
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669
Summary for 6EYI
Entry DOI | 10.2210/pdb6eyi/pdb |
Descriptor | E-selectin, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, ... (5 entities in total) |
Functional Keywords | cell adhesion, cell-adhesion molecule, c-type lectin, inflammation, leukocyte, glycomimetic, catch-bond |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33553.10 |
Authors | Jakob, R.P.,Zihlmann, P.,Preston, R.C.,Varga, N.,Ernst, B.,Maier, T. (deposition date: 2017-11-13, release date: 2018-11-21, Last modification date: 2024-11-13) |
Primary citation | Varga, N.,Zihlmann, P.,Preston, R.C.,Jakob, R.P.,Maier, T.,Ernst, B. E-selectin lectin with different glycomimetic ligands To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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