6EYI

E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand BW69669

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CkCdpGfsGLkC

Chain	Residue	Details
A	CYS142-CYS153

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site_id	PS00615
Number of Residues	28
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVeiyikrekdvgmWNDERCskkkl.ALC

Chain	Residue	Details
A	CYS90-CYS117

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site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CkCdpGFsglk....C

Chain	Residue	Details
A	CYS142-CYS153

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:1ESL, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY

Chain	Residue	Details
A	GLU80

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:11081633, ECO:0000269|PubMed:26117840, ECO:0007744|PDB:1ESL, ECO:0007744|PDB:1G1T, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY

Chain	Residue	Details
A	ASN82
A	ASN105
A	ASP106

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:11081633, ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY

Chain	Residue	Details
A	GLU88

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY

Chain	Residue	Details
A	GLU92

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site_id	SWS_FT_FI5
Number of Residues	7
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26117840, ECO:0007744|PDB:4C16, ECO:0007744|PDB:4CSY

Chain	Residue	Details
A	ASN4
A	ASN124
A	ASN139
A	ASN158
A	ASN178
A	ASN182
A	ASN244

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