5HYU
Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M2 protein
Summary for 5HYU
| Entry DOI | 10.2210/pdb5hyu/pdb |
| Related | 5HYP 5HYT 5HZP 5I0Q |
| Descriptor | M protein, serotype 2.1, C4b-binding protein alpha chain (3 entities in total) |
| Functional Keywords | m protein, complement, streptococcus pyogenes, hypervariable antigen, immune system |
| Biological source | Streptococcus pyogenes More |
| Total number of polymer chains | 2 |
| Total formula weight | 26923.04 |
| Authors | Buffalo, C.Z.,Bahn-Suh, A.J.,Ghosh, P. (deposition date: 2016-02-01, release date: 2016-07-20, Last modification date: 2019-12-11) |
| Primary citation | Buffalo, C.Z.,Bahn-Suh, A.J.,Hirakis, S.P.,Biswas, T.,Amaro, R.E.,Nizet, V.,Ghosh, P. Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1:16155-16155, 2016 Cited by PubMed: 27595425DOI: 10.1038/nmicrobiol.2016.155 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.561 Å) |
Structure validation
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