5HYU

Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M2 protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	M protein, serotype 2.1	polymer	105	12759.1	1	UniProt (P50468)	Streptococcus pyogenes
2	B (B)	C4b-binding protein alpha chain	polymer	128	14163.9	1	UniProt (P04003) Pfam (PF00084)	Homo sapiens (Human)	C4bp,Proline-rich protein,PRP
3	C, D (A, B)	water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 42 - 142 (UniProt: P50468)

PDB	External Database	Details
Gly 38	-	expression tag
Pro 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag

B: 1 - 124 (UniProt: P04003)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	26923.0
All*	Total formula weight	26923.0

*Water molecules are not included.