6XZ6

Structure of the trypanosome brucei factor H receptor bound to domain D5 of bovine factor H

Summary for 6XZ6

Entry DOI	10.2210/pdb6xz6/pdb
Descriptor	GARP domain-containing protein, Complement factor H (3 entities in total)
Functional Keywords	trypanosome brucei, immunity, complement system, factor h, factor h receptor, immune system
Biological source	Trypanosoma brucei brucei TREU927 More
Total number of polymer chains	4
Total formula weight	63572.08
Authors	Macleod, O.J.S.,Carrington, M.,Higgins, M.K. (deposition date: 2020-02-02, release date: 2020-03-25, Last modification date: 2024-01-24)
Primary citation	Macleod, O.J.S.,Bart, J.M.,MacGregor, P.,Peacock, L.,Savill, N.J.,Hester, S.,Ravel, S.,Sunter, J.D.,Trevor, C.,Rust, S.,Vaughan, T.J.,Minter, R.,Mohammed, S.,Gibson, W.,Taylor, M.C.,Higgins, M.K.,Carrington, M. A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies. Nat Commun, 11:1326-1326, 2020 Cited by PubMed: 32165615 DOI: 10.1038/s41467-020-15125-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation