PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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5MAM	Human insulin in complex with serotonin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2016-11-03 公開日 2017-04-05 最終更新日 2017-05-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MWQ	Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution 分子名称: Insulin 著者 Bocian, W, Kozerski, L. 登録日 2017-01-19 公開日 2018-02-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Lysine mis-incorporation at asparagine position during recombinant proteins production in E. coli To Be Published
5MT9	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-07 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT3	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-06 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
1JCA	Non-standard Design of Unstable Insulin Analogues with Enhanced Activity 分子名称: ZINC ION, insulin a, insulin b 著者 Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. 登録日 2001-06-08 公開日 2001-06-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
1K3M	NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES 分子名称: INSULIN 著者 Xu, B, Hua, Q.-X, Nakagawa, S.H, Jia, W, Chu, Y.-C, Katsoyannis, P.G, Weiss, M.A. 登録日 2001-10-03 公開日 2001-10-17 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci., 11, 2002
1KMF	NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES 分子名称: Insulin 著者 Xu, B, Hua, Q.X, Nakagawa, S.H, Jia, W, Chu, Y.C, Katsoyannis, P.G, Weiss, M.A. 登録日 2001-12-14 公開日 2002-01-09 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue. J.Mol.Biol., 316, 2002
1LPH	LYS(B28)PRO(B29)-HUMAN INSULIN 分子名称: CHLORIDE ION, INSULIN, PHENOL, ... 著者 Ciszak, E, Beals, J.M, Frank, B.H, Baker, J.C, Carter, N.D, Smith, G.D. 登録日 1995-04-19 公開日 1996-06-20 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin. Structure, 3, 1995
1LKQ	NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-GLY, VAL-A3-GLY, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES 分子名称: INSULIN 著者 Weiss, M.A, Hua, Q.X, Chu, Y.C, Jia, W, Philips, N.F, Wang, R.Y, Katsoyannis, P.G. 登録日 2002-04-25 公開日 2002-05-22 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing J.Biol.Chem., 277, 2002
1M5A	Crystal Structure of 2-Co(2+)-Insulin at 1.2A Resolution 分子名称: COBALT (II) ION, INSULIN A CHAIN, INSULIN B CHAIN 著者 Nicholson, J.M, Perkins, L.C, Korber, F.C. 登録日 2002-07-09 公開日 2002-08-14 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 The high-resolution structure of hexameric T6 cobalt insulin: A possible pathway for the T to R transition. Recent Research Developments in Molecular Biology, 3, 2006
1MHI	THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS 分子名称: INSULIN 著者 Jorgensen, A.M.M, Kristensen, S.M, Led, J.J, Balschmidt, P. 登録日 1994-11-30 公開日 1995-10-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of an insulin dimer. A study of the B9(Asp) mutant of human insulin using nuclear magnetic resonance, distance geometry and restrained molecular dynamics. J.Mol.Biol., 227, 1992
1MPJ	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: CHLORIDE ION, PHENOL, PHENOL INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
1MHJ	SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN 分子名称: INSULIN 著者 Jorgensen, A.M.M, Olsen, H.B, Led, J.J, Balschmidt, P. 登録日 1994-11-30 公開日 1995-10-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin. J.Mol.Biol., 257, 1996
1MSO	T6 Human Insulin at 1.0 A Resolution 分子名称: Insulin A-Chain, Insulin B-Chain, ZINC ION 著者 Smith, G.D, Pangborn, W.A, Blessing, R.H. 登録日 2002-09-19 公開日 2003-03-04 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 The structure of T6 human insulin at 1.0 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
1OS3	Dehydrated T6 human insulin at 100 K 分子名称: CHLORIDE ION, Insulin, ZINC ION 著者 Smith, G.D, Blessing, R.H. 登録日 2003-03-18 公開日 2003-07-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Lessons from an aged, dried crystal of T(6) human insulin. Acta Crystallogr.,Sect.D, 59, 2003
1OS4	Dehydrated T6 human insulin at 295 K 分子名称: Insulin, ZINC ION 著者 Smith, G.D, Blessing, R.H. 登録日 2003-03-18 公開日 2003-07-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Lessons from an aged, dried crystal of T(6) human insulin. Acta Crystallogr.,Sect.D, 59, 2003
6P4Z	Structure of gadolinium-caged cobalt (III) insulin hexamer 分子名称: CHLORIDE ION, COBALT (II) ION, GADOLINIUM ATOM, ... 著者 Tran, T.H, Taylor, S.K, Stojanovic, M.N, Tong, L. 登録日 2019-05-29 公開日 2019-06-12 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore ChemBioChem, 24, 2018
2BN3	Insulin before a high dose x-ray burn 分子名称: INSULIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
2BN1	Insulin after a high dose x-ray burn 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-18 公開日 2005-09-07 最終更新日 2013-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
1WAV	CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN 分子名称: INSULIN, PHENOL, ZINC ION 著者 Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L. 登録日 1996-02-28 公開日 1997-02-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular replacement study on form-B monoclinic crystal of insulin. Sci.China, Ser.C: Life Sci., 39, 1996
1W8P	Structural properties of the B25Tyr-NMe-B26Phe insulin mutant. 分子名称: INSULIN A-CHAIN, INSULIN B-CHAIN, PHENOL, ... 著者 Zakowa, L, Au-Alvarez, O, Dodson, E.J, Dodson, G.G, Brzozowski, A.M. 登録日 2004-09-24 公開日 2005-02-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Towards the Insulin-Igf-I Intermediate Structures: Functional and Structural Properties of the B25Tyr-Nme-B26Phe Insulin Mutant. Biochemistry, 43, 2004
1VKT	HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES 分子名称: INSULIN 著者 Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. 登録日 1996-10-14 公開日 1997-04-01 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
4I5Z	Insulin protein crystallization via langmuir-blodgett 分子名称: Insulin 著者 Belmonte, L, Pechkova, E, Bragazzi, N, Nicolini, C. 登録日 2012-11-29 公開日 2013-11-20 最終更新日 2015-12-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A review of the strategies for obtaining high-quality crystals utilizing nanotechnologies and microgravity Crit Rev Eukaryot Gene Expr, 24, 2014
4I5Y	Insulin protein crystallization via langmuir-blodgett 分子名称: Insulin 著者 Belmonte, L, Pechkova, E, Bragazzi, N, Nicolini, C. 登録日 2012-11-29 公開日 2013-11-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Review OF THE STRATEGIES FOR OBTAINING HIGH QUALITY CRYSTALS UTILIZING NANOTECHNOLOGIES AND SPACE CRIT.REV.EUKARYOT.GENE EXPR., 2013
4IDW	Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy 分子名称: Insulin A chain, Insulin B chain, ZINC ION 著者 Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B. 登録日 2012-12-13 公開日 2013-06-05 実験手法 POWDER DIFFRACTION 主引用文献 High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin Acta Crystallogr.,Sect.D, 69, 2013

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