1KMF

NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES

Summary for 1KMF

Related1K3M
DescriptorInsulin (2 entities in total)
Functional Keywordshormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5794.59
Authors
Xu, B.,Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2001-12-14, release date: 2002-01-09, Last modification date: 2011-07-13)
Primary citation
Xu, B.,Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A.
Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
J.Mol.Biol., 316:435-441, 2002
PubMed: 11866509 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2001.5377
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers485.7%25.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report