1MHJ

SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN

Summary for 1MHJ

DescriptorINSULIN (2 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5670.48
Authors
Jorgensen, A.M.M.,Olsen, H.B.,Led, J.J.,Balschmidt, P. (deposition date: 1994-11-30, release date: 1995-10-15, Last modification date: 2017-11-29)
Primary citation
Jorgensen, A.M.,Olsen, H.B.,Balschmidt, P.,Led, J.J.
Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin.
J.Mol.Biol., 257:684-699, 1996
PubMed: 8648633 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1996.0194
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers5521.3%23.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures