1LKQ

NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-GLY, VAL-A3-GLY, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES

Summary for 1LKQ

DescriptorINSULIN (2 entities in total)
Functional Keywordshormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5696.41
Authors
Weiss, M.A.,Hua, Q.X.,Chu, Y.C.,Jia, W.,Philips, N.F.,Wang, R.Y.,Katsoyannis, P.G. (deposition date: 2002-04-25, release date: 2002-05-22, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Chu, Y.C.,Jia, W.,Phillips, N.F.,Wang, R.Y.,Katsoyannis, P.G.,Weiss, M.A.
Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing
J.Biol.Chem., 277:43443-43453, 2002
PubMed: 12196530 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M206107200
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers497.5%26.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report