1LKQ
NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-GLY, VAL-A3-GLY, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 20 STRUCTURES
Summary for 1LKQ
Entry DOI | 10.2210/pdb1lkq/pdb |
Descriptor | INSULIN (2 entities in total) |
Functional Keywords | hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5696.41 |
Authors | Weiss, M.A.,Hua, Q.X.,Chu, Y.C.,Jia, W.,Philips, N.F.,Wang, R.Y.,Katsoyannis, P.G. (deposition date: 2002-04-25, release date: 2002-05-22, Last modification date: 2021-10-27) |
Primary citation | Hua, Q.X.,Chu, Y.C.,Jia, W.,Phillips, N.F.,Wang, R.Y.,Katsoyannis, P.G.,Weiss, M.A. Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing J.Biol.Chem., 277:43443-43453, 2002 Cited by PubMed: 12196530DOI: 10.1074/jbc.M206107200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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