5WWI
 
 | | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2017-01-01 | | Release date: | 2018-01-17 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (3.194 Å) | | Cite: | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1).
To Be Published
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5WXC
 | | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 2) | | Descriptor: | Beta-2-microglobulin, H7-25-F, HLA class I histocompatibility antigen, ... | | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2017-01-07 | | Release date: | 2018-01-17 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (2.295 Å) | | Cite: | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Mbio, 9, 2018
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5WXD
 | | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) | | Descriptor: | Beta-2-microglobulin, H7-25, HLA class I histocompatibility antigen, ... | | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2017-01-07 | | Release date: | 2018-01-17 | | Last modified: | 2019-07-31 | | Method: | X-RAY DIFFRACTION (3.295 Å) | | Cite: | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Mbio, 9, 2018
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4WY4
 | | Crystal structure of autophagic SNARE complex | | Descriptor: | Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8 | | Authors: | Zhao, M, Brunger, A.T. | | Deposit date: | 2014-11-15 | | Release date: | 2015-02-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
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3J96
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) | | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3J94
 | | Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3J99
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb) | | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3J98
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) | | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (8.4 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3FQ9
 | | Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications | | Descriptor: | Insulin, ZINC ION | | Authors: | Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. | | Deposit date: | 2009-01-07 | | Release date: | 2009-08-04 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
J.Biol.Chem., 284, 2009
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3J97
 | | Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II) | | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3Q25
 | | Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) | | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | Deposit date: | 2010-12-19 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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3Q29
 | | Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP) | | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | Deposit date: | 2010-12-19 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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3J95
 | | Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Vesicle-fusing ATPase | | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | | Deposit date: | 2014-12-05 | | Release date: | 2015-01-28 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
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3SEU
 | | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form III) | | Descriptor: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3SEX
 | | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | | Descriptor: | IODIDE ION, Maltose-binding periplasmic protein, NICKEL (II) ION, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3Q28
 | | Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP) | | Descriptor: | Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | Deposit date: | 2010-12-19 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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4E0O
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | Authors: | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | | Deposit date: | 2012-03-04 | | Release date: | 2012-12-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3Q27
 | | Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP) | | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | Deposit date: | 2010-12-19 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.302 Å) | | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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3SEY
 | | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | | Descriptor: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3Q26
 | | Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP) | | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein/alpha-synuclein chimeric protein, SULFATE ION, ... | | Authors: | Zhao, M, Sawaya, M.R, Cascio, D, Eisenberg, D. | | Deposit date: | 2010-12-19 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20, 2011
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3SEW
 | | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | | Descriptor: | CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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4E0M
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | Authors: | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | | Deposit date: | 2012-03-04 | | Release date: | 2013-02-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Out-of-register beta-sheets suggest a pathway
to toxic amyloid aggregates
Proc.Natl.Acad.Sci.USA, 109, 2012
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3SET
 | | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | | Descriptor: | Maltose-binding periplasmic protein, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3SEV
 | | Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization | | Descriptor: | CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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4E0N
 | | SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form II) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION | | Authors: | Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. | | Deposit date: | 2012-03-04 | | Release date: | 2012-12-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
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