Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)

Summary for 3Q29

Related3Q25 3Q26 3Q27 3Q28
Related PRD IDPRD_900001
DescriptorMaltose-binding periplasmic protein/alpha-synuclein chimeric protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, GLYCEROL, ... (5 entities in total)
Functional Keywordsfusion protein, amyloid, sugar binding protein, protein fibril
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight87502.45
Zhao, M.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2010-12-19, release date: 2011-06-01, Last modification date: 2020-07-29)
Primary citation
Zhao, M.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.
Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20:996-1004, 2011
PubMed: 21462277 (PDB entries with the same primary citation)
DOI: 10.1002/pro.630
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2306 0.4% 1.8% 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-11-25