Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)

Summary for 3Q29

Related3Q25 3Q26 3Q27 3Q28
DescriptorMaltose-binding periplasmic protein/alpha-synuclein chimeric protein, MALTOSE, SULFATE ION, ... (5 entities in total)
Functional Keywordsfusion protein, amyloid, sugar binding protein, protein fibril
Biological sourceEscherichia coli
Cellular locationCytoplasm, cytosol  P37840
Total number of polymer chains2
Total molecular weight87502.45
Zhao, M.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. (deposition date: 2010-12-19, release date: 2011-06-01, Last modification date: 2017-08-02)
Primary citation
Zhao, M.,Cascio, D.,Sawaya, M.R.,Eisenberg, D.
Structures of segments of alpha-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation
Protein Sci., 20:996-1004, 2011
PubMed: 21462277 (PDB entries with the same primary citation)
DOI: 10.1002/pro.630
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23060.4%1.8%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report