5MAM

Human insulin in complex with serotonin

Summary for 5MAM

• Entry DOI: 10.2210/pdb5mam/pdb
• Descriptor: Insulin A chain, Insulin B chain, ZINC ION, ... (6 entities in total)
• Functional Keywords: hormone, serotonin, complex, specificity
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 32
• Total formula weight: 96356.32

Authors

Brzozowski, A.M.,Turkenburg, J.P.,Jiracek, J.,Zakova, L. (deposition date: 2016-11-03, release date: 2017-04-05, Last modification date: 2017-05-31)

• Primary citation: Palivec, V.,Viola, C.M.,Kozak, M.,Ganderton, T.R.,Krizkova, K.,Turkenburg, J.P.,Haluskova, P.,Zakova, L.,Jiracek, J.,Jungwirth, P.,Brzozowski, A.M.; Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.; J. Biol. Chem., 292:8342-8355, 2017; PubMed: 28348075; DOI: 10.1074/jbc.M117.775924

Experimental method

X-RAY DIFFRACTION (2.2 Å)