5MWQ

Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution

Summary for 5MWQ

DescriptorInsulin (2 entities in total)
Functional Keywordshuman insulin, water/acetonitrile solution, mutant, biosynthetic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight6119.1
Authors
Bocian, W.,Kozerski, L. (deposition date: 2017-01-19, release date: 2018-02-14, Last modification date: 2019-05-08)
Primary citation
Stadnik, D.,Bierczynska-Krzysik, A.,Zielinska, J.,Antosik, J.,Borowicz, P.,Bocian, W.,Sitkowski, J.,Bednarek, E.,Kozerski, L.
Lysine mis-incorporation at asparagine position during recombinant proteins production in E. coli
To Be Published,
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers0 2.1% 5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures