5MWQ

Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Insulin	polymer	21	2398.8	1	UniProt (P01308)	Homo sapiens (Human)
2	B (B)	Insulin	polymer	32	3720.3	1	UniProt (P01308) Pfam (PF00049)	Homo sapiens (Human)

Sequence modifications

A: 1 - 21 (UniProt: P01308)

PDB	External Database	Details
Lys 21	Asn 110	engineered mutation

B: 1 - 32 (UniProt: P01308)

PDB	External Database	Details
Lys 31	Arg 55	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	6119.1
All*	Total formula weight	6119.1

*Water molecules are not included.