1LPH

LYS(B28)PRO(B29)-HUMAN INSULIN

Summary for 1LPH

DescriptorINSULIN, ZINC ION, PHENOL, ... (6 entities in total)
Functional Keywordsinsulin analogue, hormone, glucose metabolism
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11895.68
Authors
Ciszak, E.,Beals, J.M.,Frank, B.H.,Baker, J.C.,Carter, N.D.,Smith, G.D. (deposition date: 1995-04-19, release date: 1996-06-20, Last modification date: 2011-07-13)
Primary citation
Ciszak, E.,Beals, J.M.,Frank, B.H.,Baker, J.C.,Carter, N.D.,Smith, G.D.
Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin.
Structure, 3:615-622, 1995
PubMed: 8590022 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(01)00195-2
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers273.2%16.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution