Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2HV8
DownloadVisualize
BU of 2hv8 by Molmil
Crystal structure of GTP-bound Rab11 in complex with FIP3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eathiraj, S, Mishra, A, Prekeris, R, Lambright, D.G.
Deposit date:2006-07-27
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
J.Mol.Biol., 364, 2006
1X86
DownloadVisualize
BU of 1x86 by Molmil
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
Descriptor: PHOSPHATE ION, Rho guanine nucleotide exchange factor 12, Transforming protein RhoA
Authors:Kristelly, R, Gao, G, Tesmer, J.J.
Deposit date:2004-08-17
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
1XD2
DownloadVisualize
BU of 1xd2 by Molmil
Crystal Structure of a ternary Ras:SOS:Ras*GDP complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
Deposit date:2004-09-03
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
2G77
DownloadVisualize
BU of 2g77 by Molmil
Crystal Structure of Gyp1 TBC domain in complex with Rab33 GTPase bound to GDP and AlF3
Descriptor: ALUMINUM FLUORIDE, GTPase-activating protein GYP1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Pan, X, Eathiraj, S, Munson, M, Lambright, D.G.
Deposit date:2006-02-27
Release date:2006-07-25
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
Nature, 442, 2006
1WA5
DownloadVisualize
BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
Authors:Stewart, M.
Deposit date:2004-10-23
Release date:2004-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
6A3A
DownloadVisualize
BU of 6a3a by Molmil
MVM NES mutant Nm2 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
1VG9
DownloadVisualize
BU of 1vg9 by Molmil
The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-23
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
6A3E
DownloadVisualize
BU of 6a3e by Molmil
MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
6A3C
DownloadVisualize
BU of 6a3c by Molmil
MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
2H7V
DownloadVisualize
BU of 2h7v by Molmil
Co-crystal structure of YpkA-Rac1
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Migration-inducing protein 5, ...
Authors:Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E.
Deposit date:2006-06-04
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
6A3B
DownloadVisualize
BU of 6a3b by Molmil
MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ...
Authors:Sun, Q, Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.
Int J Nanomedicine, 16, 2021
1VG0
DownloadVisualize
BU of 1vg0 by Molmil
The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
Descriptor: CHLORIDE ION, GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-22
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
2FU5
DownloadVisualize
BU of 2fu5 by Molmil
structure of Rab8 in complex with MSS4
Descriptor: BETA-MERCAPTOETHANOL, Guanine nucleotide exchange factor MSS4, Ras-related protein Rab-8A, ...
Authors:Itzen, A, Pylypenko, O, Goody, R.S, Rak, A.
Deposit date:2006-01-26
Release date:2006-04-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nucleotide exchange via local protein unfolding-structure of Rab8 in complex with MSS4
Embo J., 25, 2006
6AXG
DownloadVisualize
BU of 6axg by Molmil
Structure of RasGRP4 in complex with HRas
Descriptor: GTPase HRas, RAS guanyl-releasing protein 4
Authors:Kondo, Y, Iwig, J.S, Kuriyan, J.
Deposit date:2017-09-06
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Elife, 6, 2017
5ZHX
DownloadVisualize
BU of 5zhx by Molmil
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2018-03-13
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YU6
DownloadVisualize
BU of 5yu6 by Molmil
CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX
Descriptor: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ...
Authors:Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E.
Deposit date:2017-11-20
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
5Z2M
DownloadVisualize
BU of 5z2m by Molmil
Structure of Orp1L/Rab7 complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Oxysterol-binding protein-related protein 1, ...
Authors:Ma, X.L, Liu, K, Li, J, Li, H.H, Li, J, Yang, C.L, Liang, H.H.
Deposit date:2018-01-03
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.142 Å)
Cite:A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning.
J. Biol. Chem., 293, 2018
6AXF
DownloadVisualize
BU of 6axf by Molmil
Structure of RasGRP2 in complex with Rap1B
Descriptor: RAS guanyl-releasing protein 2, Ras-related protein Rap-1b
Authors:Kondo, Y, Iwig, J.S, Kuriyan, J.
Deposit date:2017-09-06
Release date:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Elife, 6, 2017
1YHN
DownloadVisualize
BU of 1yhn by Molmil
Structure basis of RILP recruitment by Rab7
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab interacting lysosomal protein, ...
Authors:Wu, M, Wang, T, Hong, W, Song, H.
Deposit date:2005-01-10
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
6BCB
DownloadVisualize
BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BC0
DownloadVisualize
BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
5ZPU
DownloadVisualize
BU of 5zpu by Molmil
LFS829 in complex with CRM1-Ran-RanBP1
Descriptor: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ...
Authors:Sun, Q, Lei, Y.
Deposit date:2018-04-16
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:To be published
To Be Published
1XCG
DownloadVisualize
BU of 1xcg by Molmil
Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF
Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S.
Deposit date:2004-09-01
Release date:2004-12-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
6BC1
DownloadVisualize
BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BCA
DownloadVisualize
BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018

223532

PDB entries from 2024-08-07

PDB statisticsPDBj update infoContact PDBjnumon