Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 7 results

2ACX
DownloadVisualize
BU of 2acx by Molmil
Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP
Descriptor: G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J.
Deposit date:2005-07-19
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs.
J.Biol.Chem., 281, 2006
1TXD
DownloadVisualize
BU of 1txd by Molmil
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 12
Authors:Kristelly, R, Gao, G, Tesmer, J.J.
Deposit date:2004-07-03
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
1X86
DownloadVisualize
BU of 1x86 by Molmil
Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
Descriptor: PHOSPHATE ION, Rho guanine nucleotide exchange factor 12, Transforming protein RhoA
Authors:Kristelly, R, Gao, G, Tesmer, J.J.
Deposit date:2004-08-17
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
3PSC
DownloadVisualize
BU of 3psc by Molmil
Bovine GRK2 in complex with Gbetagamma subunits
Descriptor: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Authors:Thal, D.M, Tesmer, J.J.
Deposit date:2010-12-01
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
3PVU
DownloadVisualize
BU of 3pvu by Molmil
Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD101)
Descriptor: 3-({[4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]methyl}amino)-N-[2-(trifluoromethyl)benzyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Thal, D.M, Tesmer, J.J.
Deposit date:2010-12-07
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
3PVW
DownloadVisualize
BU of 3pvw by Molmil
Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD103A)
Descriptor: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Thal, D.M, Tesmer, J.J.
Deposit date:2010-12-07
Release date:2011-06-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol.Pharmacol., 80, 2011
6D8Z
DownloadVisualize
BU of 6d8z by Molmil
Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio
Descriptor: Triple functional domain protein
Authors:Bandekar, S, Tesmer, J.J.
Deposit date:2018-04-27
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Sci Signal, 12, 2019

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon