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PDB: 4 results

6D8Z
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BU of 6d8z by Molmil
Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio
Descriptor: Triple functional domain protein
Authors:Bandekar, S, Tesmer, J.J.
Deposit date:2018-04-27
Release date:2019-02-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Sci Signal, 12, 2019
8FIA
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BU of 8fia by Molmil
The structure of fly Teneurin self assembly
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bandekar, S.J, Li, J, Arac, D.
Deposit date:2022-12-15
Release date:2023-05-03
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers.
Embo Rep., 24, 2023
7SJ4
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BU of 7sj4 by Molmil
Human Trio residues 1284-1959 in complex with Rac1
Descriptor: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein
Authors:Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G.
Deposit date:2021-10-15
Release date:2022-07-06
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.
J.Biol.Chem., 298, 2022
8DJG
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BU of 8djg by Molmil
ADGRL3-lectin domain in complex with an activating synthetic antibody fragment
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoform 2 of Adhesion G protein-coupled receptor L3, ...
Authors:Kordon, S.P, Bandekar, S.J, Arac, D.
Deposit date:2022-06-30
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
Nat Commun, 14, 2023

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