8DJG
ADGRL3-lectin domain in complex with an activating synthetic antibody fragment
Summary for 8DJG
| Entry DOI | 10.2210/pdb8djg/pdb |
| Descriptor | sAB Heavy Chain, sAB Light Chain, Isoform 2 of Adhesion G protein-coupled receptor L3, ... (7 entities in total) |
| Functional Keywords | adhesion gpcr, lectin domain, sab, signaling protein, signaling protein-immune system complex, signaling protein/immune system |
| Biological source | synthetic construct More |
| Total number of polymer chains | 6 |
| Total formula weight | 121717.78 |
| Authors | Kordon, S.P.,Bandekar, S.J.,Arac, D. (deposition date: 2022-06-30, release date: 2023-02-15, Last modification date: 2023-10-25) |
| Primary citation | Kordon, S.P.,Dutka, P.,Adamska, J.M.,Bandekar, S.J.,Leon, K.,Erramilli, S.K.,Adams, B.,Li, J.,Kossiakoff, A.A.,Arac, D. Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder. Nat Commun, 14:635-635, 2023 Cited by PubMed: 36746957DOI: 10.1038/s41467-023-36312-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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