8DJG

ADGRL3-lectin domain in complex with an activating synthetic antibody fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	sAB Heavy Chain	polymer	233	24710.6	2		synthetic construct
2	B, D	sAB Light Chain	polymer	215	23327.8	2		synthetic construct
3	E, F	Isoform 2 of Adhesion G protein-coupled receptor L3	polymer	109	12531.2	2	UniProt (Q9HAR2) Pfam (PF02140) In PDB	Homo sapiens (human)	Calcium-independent alpha-latrotoxin receptor 3,CIRL-3,Latrophilin-3,Lectomedin-3
4	A, C, D	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	D	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7		water	water		18.0	7	Chemie (HOH)

Sequence modifications

E, F: 24 - 126 (UniProt: Q9HAR2)

PDB	External Database	Details
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	121139.3
Non-Polymers*	Number of molecules	6
	Total formula weight	578.5
All*	Total formula weight	121717.8

*Water molecules are not included.