6AXF

Structure of RasGRP2 in complex with Rap1B

Summary for 6AXF

• Entry DOI: 10.2210/pdb6axf/pdb
• Descriptor: RAS guanyl-releasing protein 2, Ras-related protein Rap-1b (2 entities in total)
• Functional Keywords: signaling protein, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytosol: Q7LDG7; Cell membrane: P61224
• Total number of polymer chains: 16
• Total formula weight: 520238.63

Authors

Kondo, Y.,Iwig, J.S.,Kuriyan, J. (deposition date: 2017-09-06, release date: 2017-10-11)

• Primary citation: Vercoulen, Y.,Kondo, Y.,Iwig, J.S.,Janssen, A.,White, K.A.,Amini, M.,Barber, D.L.,Kuriyan, J.,Roose, J.P.; A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.; Elife, 6:-, 2017; PubMed: 28952923; DOI: 10.7554/eLife.29002

Experimental method

X-RAY DIFFRACTION (3.1 Å)