2FU5

structure of Rab8 in complex with MSS4

Summary for 2FU5

Entry DOI	10.2210/pdb2fu5/pdb
Descriptor	Guanine nucleotide exchange factor MSS4, Ras-related protein Rab-8A, ZINC ION, ... (5 entities in total)
Functional Keywords	mss4:rab8 protein complex, gef:gtpase nucleotide free complex, nucleotide exchange via unfolding of nucleotide binding region, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane ; Lipid-anchor ; Cytoplasmic side : P55258
Total number of polymer chains	4
Total formula weight	68589.42
Authors	Itzen, A.,Pylypenko, O.,Goody, R.S.,Rak, A. (deposition date: 2006-01-26, release date: 2006-04-04, Last modification date: 2023-10-25)
Primary citation	Itzen, A.,Pylypenko, O.,Goody, R.S.,Alexandrov, K.,Rak, A. Nucleotide exchange via local protein unfolding-structure of Rab8 in complex with MSS4 Embo J., 25:1445-1455, 2006 Cited by PubMed: 16541104 DOI: 10.1038/sj.emboj.7601044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation