1VG9

The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein

Summary for 1VG9

Entry DOI	10.2210/pdb1vg9/pdb
Related	1LTX 1VG0 1VG1 1VG8
Descriptor	Rab proteins geranylgeranyltransferase component A 1, Ras-related protein Rab-7, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	rab prenylation, post-translational modification, protein binding-protein transport complex, protein binding/protein transport
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Cytoplasm, cytosol : P37727 Cytoplasmic vesicle, phagosome membrane ; Peripheral membrane protein ; Cytoplasmic side : P09527
Total number of polymer chains	8
Total formula weight	378304.88
Authors	Rak, A.,Pylypenko, O.,Niculae, A.,Pyatkov, K.,Goody, R.S.,Alexandrov, K. (deposition date: 2004-04-23, release date: 2004-07-20, Last modification date: 2023-10-25)
Primary citation	Rak, A.,Pylypenko, O.,Niculae, A.,Pyatkov, K.,Goody, R.S.,Alexandrov, K. Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease Cell(Cambridge,Mass.), 117:749-760, 2004 Cited by PubMed: 15186776 DOI: 10.1016/j.cell.2004.05.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation