1VG9
The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Rab proteins geranylgeranyltransferase component A 1 | polymer | 650 | 72622.2 | 4 | UniProt (P37727) Pfam (PF00996) Pfam (PF22603) | Rattus norvegicus (Norway rat) | Rab escort protein 1, REP-1 |
| 2 | B, D, F, H (B, D, F, H) | Ras-related protein Rab-7 | polymer | 185 | 21121.0 | 4 | UniProt (P09527) Pfam (PF00071) | Rattus norvegicus (Norway rat) | RAS-related protein P23, RAS-related protein BRL-RAS |
| 3 | I, M, Q, U (B, D, F, H) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | J, N, R, V (B, D, F, H) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | K, O, S, W (B, D, F, H) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
| 6 | L, P, T, X (B, D, F, H) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 4 | Chemie (P33) | |||
| 7 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 1042 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 650 (UniProt: P37727)
| PDB | External Database | Details |
|---|---|---|
| Lys 231 | Gln 231 | engineered mutation |
| Arg 462 | Lys 462 | engineered mutation |
| Thr 473 | Ala 473 | engineered mutation |
| Ala 483 | Gly 483 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 374972.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3331.9 | |
| All* | Total formula weight | 378304.9 |
