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PDB: 26 results

6VKF
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CCHFV GP38 (IbAr10200)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38
Authors:Mishra, A.K, McLellan, J.S.
Deposit date:2020-01-20
Release date:2020-02-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.524 Å)
Cite:Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38.
J.Virol., 94, 2020
5GO1
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Structural, Functional characterization and discovery of novel inhibitors of Leishmania amazonensis Nucleoside Diphosphatase Kinase (NDK)
Descriptor: Nucleoside diphosphate kinase
Authors:Mishra, A.K, Agnihotri, P, Singh, S.P, Pratap, J.V.
Deposit date:2016-07-26
Release date:2017-07-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of novel inhibitors for Leishmania nucleoside diphosphatase kinase (NDK) based on its structural and functional characterization.
J. Comput. Aided Mol. Des., 31, 2017
8SO3
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BU of 8so3 by Molmil
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ...
Authors:Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A.
Deposit date:2023-04-28
Release date:2023-09-06
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
8SR0
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CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ...
Authors:Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A.
Deposit date:2023-05-05
Release date:2023-09-06
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
8FWH
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Crystal structure of bivalent antibody Fab fragment of Anti-human LAG3 (22D2)
Descriptor: 1,2-ETHANEDIOL, Anti-human LAG3 (22D2) heavy chain, Anti-human LAG3 (22D2) light chain
Authors:Mishra, A.K, Agnihotri, P, Mariuzza, R.A.
Deposit date:2023-01-22
Release date:2023-09-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.833 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
4IRU
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BU of 4iru by Molmil
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Descriptor: ACETATE ION, ALUMINUM FLUORIDE, GLYCEROL, ...
Authors:Mishra, A.K, Delcampo, C.M, Collins, R.E, Roy, C.R, Lambright, D.G.
Deposit date:2013-01-15
Release date:2013-07-10
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism.
J.Biol.Chem., 288, 2013
2QKD
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BU of 2qkd by Molmil
Crystal structure of tandem ZPR1 domains
Descriptor: FORMIC ACID, ZINC ION, Zinc finger protein ZPR1
Authors:Mishra, A.K.
Deposit date:2007-07-10
Release date:2007-08-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3MJH
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BU of 3mjh by Molmil
Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1
Descriptor: Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Mishra, A.K, Eathiraj, S, Lambright, D.G.
Deposit date:2010-04-12
Release date:2010-05-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
Proc.Natl.Acad.Sci.USA, 107, 2010
7L7R
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BU of 7l7r by Molmil
CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs
Descriptor: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain, ADI-37801 Fab heavy chain, ...
Authors:Mishra, A.K, McLellan, J.S.
Deposit date:2020-12-30
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
7KX4
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Anti-CCHFV ADI-36121 Fab
Descriptor: ADI-36121 Fab heavy chain, ADI-36121 Fab light chain
Authors:Mishra, A.K, McLellan, J.S.
Deposit date:2020-12-03
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Science, 375, 2022
6WKM
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BU of 6wkm by Molmil
Fab Fragment of Anti-human LAG3 antibody (22D2)
Descriptor: 22D2 Fab Heavy Chain, 22D2 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 2023
6WJU
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BU of 6wju by Molmil
Fab Fragment of Anti-human LAG3 antibody (4A10)
Descriptor: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-14
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WK4
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BU of 6wk4 by Molmil
Fab Fragment of Anti-human LAG3 antibody (13E2)
Descriptor: 13E2 Fab Heavy Chain, 13E2 Fab Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-15
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKL
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BU of 6wkl by Molmil
Fab Fragment of Anti-human LAG3 antibody (BAP050)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
2HV8
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BU of 2hv8 by Molmil
Crystal structure of GTP-bound Rab11 in complex with FIP3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Eathiraj, S, Mishra, A, Prekeris, R, Lambright, D.G.
Deposit date:2006-07-27
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
J.Mol.Biol., 364, 2006
5X00
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BU of 5x00 by Molmil
Nucleoside Diphosphate Kinase from Vibrio cholerae is a Thermolabile Type II tetramer
Descriptor: Nucleoside diphosphate kinase
Authors:Agnihotri, P, Mishra, A.K, Pratap, J.V.
Deposit date:2017-01-19
Release date:2018-01-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Nucleoside Diphosphate Kinase from Vibrio cholerae is a Thermolabile Type II tetramer.
To Be Published
4LQ6
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BU of 4lq6 by Molmil
Crystal structure of Rv3717 reveals a novel amidase from M. tuberculosis
Descriptor: CHLORIDE ION, N-acetymuramyl-L-alanine amidase-related protein, PLATINUM (II) ION, ...
Authors:Kumar, A, Kumar, S, Kumar, D, Mishra, A, Dewangan, R.P, Shrivastava, P, Ramachandran, S, Taneja, B.
Deposit date:2013-07-17
Release date:2013-12-04
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
6IEN
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BU of 6ien by Molmil
Substrate/product bound Argininosuccinate lyase from Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, ARGININE, ARGININOSUCCINATE, ...
Authors:Paul, A, Mishra, A, Surolia, A, Vijayan, M.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
6IEM
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BU of 6iem by Molmil
Argininosuccinate lyase from Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, Argininosuccinate lyase, ...
Authors:Paul, A, Mishra, A, Surolia, A, Vijayan, M.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
6JCH
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BU of 6jch by Molmil
Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Orthorhombic form
Descriptor: Pilus assembly protein, SODIUM ION
Authors:Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V.
Deposit date:2019-01-28
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.536 Å)
Cite:Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus.
J.Struct.Biol., 207, 2019
6JBV
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BU of 6jbv by Molmil
Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Selenium derivative
Descriptor: Pilus assembly protein, SODIUM ION
Authors:Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V.
Deposit date:2019-01-26
Release date:2019-06-26
Last modified:2021-09-15
Method:X-RAY DIFFRACTION (1.712 Å)
Cite:Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus.
J.Struct.Biol., 207, 2019
6JK7
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BU of 6jk7 by Molmil
Crystal structure of SpaE basal pilin from Lactobacillus rhamnosus GG - Trigonal form
Descriptor: Pilus assembly protein
Authors:Megta, A.K, Mishra, A.K, Palva, A, von Ossowski, I, Krishnan, V.
Deposit date:2019-02-27
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus.
J.Struct.Biol., 207, 2019
4MXP
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BU of 4mxp by Molmil
Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM
Descriptor: (2R)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Defects in Rab1 recruitment protein A, SODIUM ION
Authors:Del Campo, C.M, Mishra, A.K, Wang, Y.H, Roy, C.R, Janmey, P.A, Lambright, D.G.
Deposit date:2013-09-26
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM.
Structure, 22, 2014
7LYW
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BU of 7lyw by Molmil
Crystal structure of the HCMV pentamer-specific antibody 2-25
Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain
Authors:Wrapp, D, Mishra, A.K, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
8E1B
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BU of 8e1b by Molmil
Crystal Structure of Nanobody VHH108 Specific for PA14 Cif
Descriptor: Nanobody VHH108
Authors:Simard, A.R, Taher, N.M, Mishra, A.K, Madden, D.R.
Deposit date:2022-08-10
Release date:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Nanobody VHH108 Specific for PA14 Cif
To Be Published

 

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