4IRU

Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3

Summary for 4IRU

Entry DOI	10.2210/pdb4iru/pdb
Descriptor	LepB, Ras-related protein Rab-1A, ACETATE ION, ... (9 entities in total)
Functional Keywords	arginine finger, glutamate finger, p-loop motif, nucleotide binding, intrinsic gtpase activity, gtp hydrolysis, gtp hydrolysis activator, gtpase activating protein (gap), protein transport, hydrolase-hydrolase complex, hydrolase/hydrolase
Biological source	Legionella pneumophila More
Cellular location	Golgi apparatus: P62820
Total number of polymer chains	6
Total formula weight	168608.75
Authors	Mishra, A.K.,Delcampo, C.M.,Collins, R.E.,Roy, C.R.,Lambright, D.G. (deposition date: 2013-01-15, release date: 2013-07-10, Last modification date: 2013-09-04)
Primary citation	Mishra, A.K.,Del Campo, C.M.,Collins, R.E.,Roy, C.R.,Lambright, D.G. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism. J.Biol.Chem., 288:24000-24011, 2013 Cited by PubMed: 23821544 DOI: 10.1074/jbc.M113.470625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation