4IRU
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | LepB | polymer | 299 | 33916.3 | 3 | UniProt (Q5ZSM7) Pfam (PF18172) Pfam (PF18227) In PDB | Legionella pneumophila | |
2 | B, D, F | Ras-related protein Rab-1A | polymer | 184 | 21175.2 | 3 | UniProt (P62820) Pfam (PF00071) In PDB | Homo sapiens (human) | YPT1-related protein |
3 | C, A, D, B | ACETATE ION | non-polymer | 59.0 | 12 | Chemie (ACT) | |||
4 | C, A, B | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
5 | C, A, B | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
6 | D, F, B | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
7 | D, F, B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
8 | D, F, B | ALUMINUM FLUORIDE | non-polymer | 84.0 | 3 | Chemie (AF3) | |||
9 | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, C, E: 326 - 623 (UniProt: Q5ZSM7)
B, D, F: 4 - 177 (UniProt: P62820)
PDB | External Database | Details |
---|---|---|
Ser 325 | - | EXPRESSION TAG |
PDB | External Database | Details |
---|---|---|
Mse -6 | - | EXPRESSION TAG |
Gly -5 | - | EXPRESSION TAG |
His -4 | - | EXPRESSION TAG |
His -3 | - | EXPRESSION TAG |
His -2 | - | EXPRESSION TAG |
His -1 | - | EXPRESSION TAG |
His 0 | - | EXPRESSION TAG |
His 1 | - | EXPRESSION TAG |
Gly 2 | - | EXPRESSION TAG |
Ser 3 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 165274.4 | |
Non-Polymers* | Number of molecules | 35 |
Total formula weight | 3334.3 | |
All* | Total formula weight | 168608.8 |