4IRU
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | LepB | polymer | 299 | 33916.3 | 3 | UniProt (Q5ZSM7) Pfam (PF18172) Pfam (PF18227) | Legionella pneumophila | |
| 2 | B, D, F (B, D, F) | Ras-related protein Rab-1A | polymer | 184 | 21175.2 | 3 | UniProt (P62820) Pfam (PF00071) | Homo sapiens (human) | YPT1-related protein |
| 3 | AA, BA, CA, DA, EA... (C, A, D, B) | ACETATE ION | non-polymer | 59.0 | 12 | Chemie (ACT) PubChem (175) | |||
| 4 | FA, I, J, K, L... (C, A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) PubChem (753) | |||
| 5 | GA, O, P, Q, R... (C, A, B) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) PubChem (813) | |||
| 6 | HA, MA, S (D, F, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 7 | IA, NA, T (D, F, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | JA, OA, U (D, F, B) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 3 | Chemie (AF3) PubChem (2124) | |||
| 9 | PA, QA, RA, SA, TA (A, B, C, D, F) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, C, E: 326 - 623 (UniProt: Q5ZSM7)
B, D, F: 4 - 177 (UniProt: P62820)
| PDB | External Database | Details |
|---|---|---|
| Ser 325 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Mse -6 | - | expression tag |
| Gly -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165274.4 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 3334.3 | |
| All* | Total formula weight | 168608.8 |
