4MXP

Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM

Summary for 4MXP

• Entry DOI: 10.2210/pdb4mxp/pdb
• Descriptor: Defects in Rab1 recruitment protein A, (2R)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, SODIUM ION, ... (4 entities in total)
• Functional Keywords: protein-lipid complex, guanine nucleotide exchange factor, rab1 binding, pi(4)p-binding protein
• Biological source: Legionella pneumophila subsp. pneumophila
• Cellular location: Secreted: Q5ZSQ3
• Total number of polymer chains: 1
• Total formula weight: 37691.56

Authors

Del Campo, C.M.,Mishra, A.K.,Wang, Y.H.,Roy, C.R.,Janmey, P.A.,Lambright, D.G. (deposition date: 2013-09-26, release date: 2014-03-19, Last modification date: 2023-09-20)

• Primary citation: Del Campo, C.M.,Mishra, A.K.,Wang, Y.H.,Roy, C.R.,Janmey, P.A.,Lambright, D.G.; Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM.; Structure, 22:397-408, 2014; PubMed: 24530282; DOI: 10.1016/j.str.2013.12.018

Experimental method

X-RAY DIFFRACTION (1.83 Å)