7LYW
Crystal structure of the HCMV pentamer-specific antibody 2-25
Summary for 7LYW
Entry DOI | 10.2210/pdb7lyw/pdb |
Descriptor | 2-25 Fab Heavy Chain, 2-25 Fab Light Chain (3 entities in total) |
Functional Keywords | antibody, fab, hcmv pentamer, cytomegalovirus, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 143739.54 |
Authors | Wrapp, D.,Mishra, A.K.,McLellan, J.S. (deposition date: 2021-03-08, release date: 2021-08-11, Last modification date: 2023-10-18) |
Primary citation | Wrapp, D.,Ye, X.,Ku, Z.,Su, H.,Jones, H.G.,Wang, N.,Mishra, A.K.,Freed, D.C.,Li, F.,Tang, A.,Li, L.,Jaijyan, D.K.,Zhu, H.,Wang, D.,Fu, T.M.,Zhang, N.,An, Z.,McLellan, J.S. Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8:eabm2546-eabm2546, 2022 Cited by PubMed: 35275718DOI: 10.1126/sciadv.abm2546 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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