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4FG7
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Crystal structure of human calcium/calmodulin-dependent protein kinase I 1-293 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type 1
Authors:Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
Deposit date:2012-06-04
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
4FGB
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BU of 4fgb by Molmil
Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form
Descriptor: Calcium/calmodulin-dependent protein kinase type 1
Authors:Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
Deposit date:2012-06-04
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
8KA0
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BU of 8ka0 by Molmil
Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-bound calmodulin and a nicotinamide adenine dinucleotide (NAD+)
Descriptor: CALCIUM ION, Calmodulin-2, GLYCEROL, ...
Authors:Lee, Y, Choi, S, Hwang, J, Kim, M.H.
Deposit date:2023-08-02
Release date:2024-07-10
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet.
Nat Commun, 15, 2024
8K9Z
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BU of 8k9z by Molmil
Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-bound calmodulin
Descriptor: CALCIUM ION, Calmodulin-2, RDTND-RID CBD
Authors:Lee, Y, Choi, S, Hwang, J, Kim, M.H.
Deposit date:2023-08-02
Release date:2024-07-10
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet.
Nat Commun, 15, 2024
5K8Q
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BU of 5k8q by Molmil
Crystal Structure of Calcium-loaded Calmodulin in complex with STRA6 CaMBP2-site peptide.
Descriptor: CALCIUM ION, Calmodulin, IMIDAZOLE, ...
Authors:Stowe, S.D, Clarke, O.B, Cavalier, M.C, Godoy-Ruiz, R, Mancia, F, Weber, D.J.
Deposit date:2016-05-30
Release date:2016-08-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.739 Å)
Cite:Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
2A2A
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BU of 2a2a by Molmil
High-resolution crystallographic analysis of the autoinhibited conformation of a human death-associated protein kinase
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Death-associated protein kinase 2, ...
Authors:Kursula, P, Wilmanns, M.
Deposit date:2005-06-22
Release date:2006-10-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Structure, 2016
1YRP
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BU of 1yrp by Molmil
Catalytic domain of human ZIP kinase phosphorylated at Thr265
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Death-associated protein kinase 3
Authors:Kursula, P, Vahokoski, J, Wilmanns, M.
Deposit date:2005-02-04
Release date:2006-06-20
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Structure, 2016
5DBR
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BU of 5dbr by Molmil
Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate
Descriptor: CALCIUM ION, Calmodulin, Sodium channel protein type 5 subunit alpha
Authors:Johnson, C.N, Thompson, M.K, Chazin, W.J.
Deposit date:2015-08-21
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Enhanced Understanding of Ca2+ Modulation of the Human Cardiac Sodium Channel: Tight Binding of Calmodulin to the Inactivation Gate
To Be Published
6MC9
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BU of 6mc9 by Molmil
Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin
Descriptor: CALCIUM ION, Calmodulin-1, Sodium channel protein type 4 subunit alpha
Authors:Yoder, J.B, Gabelli, S.B, Amzel, L.M.
Deposit date:2018-08-30
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
4N5X
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BU of 4n5x by Molmil
Crystal structure of N-terminal calmodulin-like Calcium sensor of human mitochondrial ATP-Mg/Pi carrier SCaMC1
Descriptor: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, DI(HYDROXYETHYL)ETHER
Authors:Yang, Q, Bruschweiler, S, Chou, J.
Deposit date:2013-10-10
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Self-Sequestered Calmodulin-like Ca(2+) Sensor of Mitochondrial SCaMC Carrier and Its Implication to Ca(2+)-Dependent ATP-Mg/Pi Transport.
Structure, 22, 2014
6SZ5
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Human calmodulin bound to a peptide of human NADPH oxidase 5
Descriptor: CALCIUM ION, Calmodulin-2, NADPH oxidase 5
Authors:Millana, E, Mattevi, A.
Deposit date:2019-10-02
Release date:2019-12-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5).
Febs J., 287, 2020
6O20
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BU of 6o20 by Molmil
Cryo-EM structure of TRPV5 with calmodulin bound
Descriptor: CALCIUM ION, Calmodulin, Transient receptor potential cation channel subfamily V member 5
Authors:Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J.
Deposit date:2019-02-22
Release date:2019-04-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insight into TRPV5 channel function and modulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
1X02
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BU of 1x02 by Molmil
Solution structure of stereo array isotope labeled (SAIL) calmodulin
Descriptor: CALCIUM ION, calmodulin
Authors:Kainosho, M, Torizawa, T, Terauchi, T, Ono, A.M, Guntert, P.
Deposit date:2005-03-11
Release date:2006-03-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Optimal isotope labelling for NMR protein structure determinations.
Nature, 440, 2006
1SK6
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BU of 1sk6 by Molmil
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin, ...
Authors:Guo, Q, Shen, Y, Zhukovskaya, N.L, Tang, W.J.
Deposit date:2004-03-04
Release date:2004-06-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
J.Biol.Chem., 279, 2004
1PK0
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BU of 1pk0 by Molmil
Crystal Structure of the EF3-CaM complexed with PMEApp
Descriptor: (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ...
Authors:Shen, Y, Tang, W.J.
Deposit date:2003-06-04
Release date:2004-02-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.
Proc.Natl.Acad.Sci.USA, 101, 2004
3OX5
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BU of 3ox5 by Molmil
Crystal Structure of the calcium sensor calcium-binding protein 1 (CaBP1)
Descriptor: CALCIUM ION, Calcium-binding protein 1
Authors:Findeisen, F, Minor, D.L.
Deposit date:2010-09-21
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for the Differential Effects of CaBP1 and Calmodulin on Ca(V)1.2 Calcium-Dependent Inactivation.
Structure, 18, 2010
3OX6
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BU of 3ox6 by Molmil
Crystal Structure of the calcium sensor calcium-binding protein 1 (CaBP1)
Descriptor: CALCIUM ION, Calcium-binding protein 1, HEXANE-1,6-DIOL
Authors:Findeisen, F, Minor, D.L.
Deposit date:2010-09-21
Release date:2010-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for the Differential Effects of CaBP1 and Calmodulin on Ca(V)1.2 Calcium-Dependent Inactivation.
Structure, 18, 2010
3I6X
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BU of 3i6x by Molmil
Crystal structure of the calponin homology domain of IQGAP1
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Kurella, V.B.
Deposit date:2009-07-07
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
2AAO
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BU of 2aao by Molmil
Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Descriptor: CALCIUM ION, Calcium-dependent protein kinase, isoform AK1
Authors:Chandran, V, Stollar, E.J, Lindorff-Larsen, K, Harper, J.F, Chazin, W.J, Dobson, C.M, Luisi, B.F, Christodoulou, J.
Deposit date:2005-07-13
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition.
J.Mol.Biol., 357, 2006
8T6K
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BU of 8t6k by Molmil
Cryo-EM structure of tetradecameric CaMKII beta holoenzyme T287A T306A T307A
Descriptor: Venus-tagged CaMKII Beta Holoenzyme mutant
Authors:Chien, C.-T, Chiu, W, Khan, S.
Deposit date:2023-06-16
Release date:2024-06-19
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Hub stability in the calcium calmodulin-dependent protein kinase II.
Commun Biol, 7, 2024
8T6Q
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BU of 8t6q by Molmil
Cryo-EM structure of dodecameric CaMKII beta holoenzyme T287A T306A T307A
Descriptor: Venus-tagged CaMKII beta holoenzyme mutant
Authors:Chien, C.-T, Chiu, W, Khan, S.
Deposit date:2023-06-16
Release date:2024-06-19
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Hub stability in the calcium calmodulin-dependent protein kinase II.
Commun Biol, 7, 2024
8TUC
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BU of 8tuc by Molmil
Unphosphorylated CaMKK2 in complex with CC-8977
Descriptor: (4M)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid, 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase kinase 2, ...
Authors:Bernard, S.M, Shanmugasundaram, V, D'Agostino, L.
Deposit date:2023-08-16
Release date:2023-12-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2).
J.Med.Chem., 66, 2023
3HBX
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BU of 3hbx by Molmil
Crystal structure of GAD1 from Arabidopsis thaliana
Descriptor: Glutamate decarboxylase 1
Authors:Gut, H, Dominici, P, Pilati, S, Gruetter, M.G, Capitani, G.
Deposit date:2009-05-05
Release date:2009-07-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.672 Å)
Cite:A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase.
J.Mol.Biol., 392, 2009
4JQ0
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BU of 4jq0 by Molmil
Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin
Descriptor: CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ...
Authors:Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S.
Deposit date:2013-03-19
Release date:2014-05-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.84 Å)
Cite:Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.
Nat Commun, 5, 2014
4JPZ
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Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin
Descriptor: CALCIUM ION, Calmodulin, Fibroblast growth factor 13, ...
Authors:Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S.
Deposit date:2013-03-19
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.
Nat Commun, 5, 2014

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