5DBR

Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate

Summary for 5DBR

• Entry DOI: 10.2210/pdb5dbr/pdb
• Descriptor: Calmodulin, Sodium channel protein type 5 subunit alpha, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: calmodulin, nav1.5, inactivation gate, metal binding protein-transport protein complex, metal binding protein/transport protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 22466.26

Authors

Johnson, C.N.,Thompson, M.K.,Chazin, W.J. (deposition date: 2015-08-21, release date: 2017-02-22, Last modification date: 2023-09-27)

• Primary citation: Johnson, C.N.,Thompson, M.K.,Voehler, M.,Chazin, W.J.; Enhanced Understanding of Ca2+ Modulation of the Human Cardiac Sodium Channel: Tight Binding of Calmodulin to the Inactivation Gate; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)