6XRZ
 
 | | The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | | Descriptor: | Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | | Authors: | Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R. | | Deposit date: | 2020-07-14 | | Release date: | 2020-08-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome.
Biorxiv, 2020
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4V94
 | | Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J. | | Deposit date: | 2012-01-11 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Structure, 20, 2012
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5NG5
 | | multi-drug efflux; membrane transport; RND superfamily; Drug resistance | | Descriptor: | 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ... | | Authors: | Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. | | Deposit date: | 2017-03-16 | | Release date: | 2017-04-19 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
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5GAI
 | | Probabilistic Structural Models of Mature P22 Bacteriophage Portal, Hub, and Tailspike proteins | | Descriptor: | Peptidoglycan hydrolase gp4, Portal protein, Tail fiber protein | | Authors: | Pintilie, G, Chen, D.H, Haase-Pettingell, C.A, King, J.A, Chiu, W. | | Deposit date: | 2015-12-01 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (10.5 Å) | | Cite: | Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage.
Biophys.J., 110, 2016
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6DJY
 | | Fako virus | | Descriptor: | Clamp protein, Major capsid protein, Turret protein | | Authors: | Kaelber, J.T, Jiang, W, Weaver, S.C, Auguste, A.J, Chiu, W. | | Deposit date: | 2018-05-27 | | Release date: | 2019-06-05 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The polymerase organization of Fako virus
To be Published
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7RRP
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8UYK
 | | MERS 5' proximal stem-loop 5, conformation 1 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYS
 | | SARS-CoV-2 5' proximal stem-loop 5 | | Descriptor: | SARS-CoV-2 RNA SL5 domain. | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-14 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYJ
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | | Descriptor: | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYM
 | | MERS 5' proximal stem-loop 5, conformation 3 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYG
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 2 | | Descriptor: | RNA (135-MER) | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYE
 | | BtCoV-HKU5 5' proximal stem-loop 5, conformation 1 | | Descriptor: | BtCoV-HKU5 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYL
 | | MERS 5' proximal stem-loop 5, conformation 2 | | Descriptor: | MERS 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYP
 | | SARS-CoV-1 5' proximal stem-loop 5 | | Descriptor: | SARS-CoV-1 5' proximal stem-loop 5 | | Authors: | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | | Deposit date: | 2023-11-13 | | Release date: | 2023-12-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses.
Proc.Natl.Acad.Sci.USA, 121, 2024
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2XYZ
 | | De Novo model of Bacteriophage P22 virion coat protein | | Descriptor: | COAT PROTEIN | | Authors: | Chen, D.-H, Baker, M.L, Hryc, C.F, DiMaio, F, Jakana, J, Wu, W, Dougherty, M, Haase-Pettingell, C, Schmid, M.F, Jiang, W, Baker, D, King, J.A, Chiu, W. | | Deposit date: | 2010-11-19 | | Release date: | 2011-02-02 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural Basis for Scaffolding-Mediated Assembly and Maturation of a DsDNA Virus.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2XYY
 | | De Novo model of Bacteriophage P22 procapsid coat protein | | Descriptor: | COAT PROTEIN | | Authors: | Chen, D.-H, Baker, M.L, Hryc, C.F, DiMaio, F, Jakana, J, Wu, W, Dougherty, M, Haase-Pettingell, C, Schmid, M.F, Jiang, W, Baker, D, King, J.A, Chiu, W. | | Deposit date: | 2010-11-19 | | Release date: | 2011-02-02 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Basis for Scaffolding-Mediated Assembly and Maturation of a DsDNA Virus.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7XSM
 | | Misfolded Tetrahymena ribozyme conformation 3 | | Descriptor: | RNA (388-MER) | | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | | Deposit date: | 2022-05-14 | | Release date: | 2022-08-03 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (4.01 Å) | | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSN
 | | Native Tetrahymena ribozyme conformation | | Descriptor: | RNA (387-MER) | | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | | Deposit date: | 2022-05-14 | | Release date: | 2022-08-03 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSL
 | | Misfolded Tetrahymena ribozyme conformation 2 | | Descriptor: | RNA (388-MER) | | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | | Deposit date: | 2022-05-14 | | Release date: | 2022-08-03 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSK
 | | Misfolded Tetrahymena ribozyme conformation 1 | | Descriptor: | RNA (388-MER) | | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | | Deposit date: | 2022-05-14 | | Release date: | 2022-08-03 | | Last modified: | 2022-10-05 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2XD8
 | | Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7 | | Descriptor: | T7-LIKE CAPSID PROTEIN | | Authors: | Liu, X, Zhang, Q, Murata, K, Baker, M.L, Sullivan, M.B, Fu, C, Dougherty, M, Schmid, M.F, Osburne, M.S, Chisholm, S.W, Chiu, W. | | Deposit date: | 2010-04-30 | | Release date: | 2010-06-16 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural Changes in a Marine Podovirus Associated with Release of its Genome Into Prochlorococcus
Nat.Struct.Mol.Biol., 17, 2010
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6C54
 | | Ebola nucleoprotein nucleocapsid-like assembly and the asymmetric unit | | Descriptor: | Nucleoprotein | | Authors: | Su, Z, Wu, C, Pintilie, G.D, Chiu, W, Amarasinghe, G.K, Leung, D.W. | | Deposit date: | 2018-01-13 | | Release date: | 2018-03-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.
Cell, 172, 2018
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7WU7
 | | Prefoldin-tubulin-TRiC complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... | | Authors: | Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. | | Deposit date: | 2022-02-07 | | Release date: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
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8FR7
 | | A hinge glycan regulates spike bending and impacts coronavirus infectivity | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Pintilie, G, Wilson, E, Chmielewski, D, Schmid, M.F, Jin, J, Chen, M, Singharoy, A, Chiu, W. | | Deposit date: | 2023-01-06 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | A hinge glycan regulates spike bending and impacts coronavirus infectivity
To Be Published
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8TA2
 | | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42 | | Descriptor: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2 | | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | | Deposit date: | 2023-06-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.
Elife, 12, 2024
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