2A2A
High-resolution crystallographic analysis of the autoinhibited conformation of a human death-associated protein kinase
Summary for 2A2A
Entry DOI | 10.2210/pdb2a2a/pdb |
Related | 2A27 |
Descriptor | Death-associated protein kinase 2, SODIUM ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | protein kinase, autoinhibition, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9UIK4 |
Total number of polymer chains | 4 |
Total formula weight | 149849.58 |
Authors | Kursula, P.,Wilmanns, M. (deposition date: 2005-06-22, release date: 2006-10-17, Last modification date: 2023-10-25) |
Primary citation | Simon, B.,Huart, A.S.,Temmerman, K.,Vahokoski, J.,Mertens, H.D.,Komadina, D.,Hoffmann, J.E.,Yumerefendi, H.,Svergun, D.I.,Kursula, P.,Schultz, C.,McCarthy, A.A.,Hart, D.J.,Wilmanns, M. Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites Structure, 2016 Cited by PubMed: 27133022DOI: 10.1016/j.str.2016.03.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
Download full validation report