1C81
| MICHAELIS COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | 2,5-anhydro-1-deoxy-1-phosphono-6-O-phosphono-D-glucitol, FRUCTOSE-2,6-BISPHOSPHATASE | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
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1C80
| REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | FRUCTOSE-2,6-BISPHOSPHATASE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
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1C7Z
| REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | FRUCTOSE-2,6-BISPHOSPHATASE, GLYCERALDEHYDE-3-PHOSPHATE, PHOSPHATE ION | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
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6TKO
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8SZP
| Human DHX9 bound to ADP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, ... | Authors: | Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. | Deposit date: | 2023-05-30 | Release date: | 2023-08-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
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8SZS
| Cat DHX9 bound to GDP | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lee, Y.-T, Sickmier, E.A, Boriack-Sjodin, P.A. | Deposit date: | 2023-05-30 | Release date: | 2023-09-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Development of assays to support identification and characterization of modulators of DExH-box helicase DHX9. Slas Discov, 28, 2023
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4XSJ
| Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-01-22 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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4XTB
| Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter | Descriptor: | Calcium uniporter protein, mitochondrial, TETRAETHYLENE GLYCOL | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-01-23 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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8KHM
| Crystal structure of human methionine aminopeptidase 12 (MAP12) in the unbound form | Descriptor: | GLYCEROL, Methionine aminopeptidase 1D, mitochondrial, ... | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | Deposit date: | 2023-08-22 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D. Sci Rep, 13, 2023
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8KHO
| Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two Cobalt ions and Methionine | Descriptor: | COBALT (II) ION, METHIONINE, Methionine aminopeptidase 1D, ... | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | Deposit date: | 2023-08-22 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D. Sci Rep, 13, 2023
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8KHN
| Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two cobalt ions | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 1D, mitochondrial, ... | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | Deposit date: | 2023-08-22 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D. Sci Rep, 13, 2023
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8SZQ
| Cat DHX9 bound to ADP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. | Deposit date: | 2023-05-30 | Release date: | 2023-08-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.711 Å) | Cite: | Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
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8SZR
| Dog DHX9 bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNA helicase, ... | Authors: | Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. | Deposit date: | 2023-05-30 | Release date: | 2023-08-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
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8J1E
| AtSLAC1 in open state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | Authors: | Lee, Y, Lee, S. | Deposit date: | 2023-04-12 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8J0J
| AtSLAC1 8D mutant in closed state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | Authors: | Lee, Y, Lee, S. | Deposit date: | 2023-04-11 | Release date: | 2023-11-22 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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7NF8
| Ovine (b0,+AT-rBAT)2 hetero-tetramer, asymmetric unit, rigid-body fitted | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lee, Y, Kuehlbrandt, W. | Deposit date: | 2021-02-05 | Release date: | 2022-01-19 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria. Nat Commun, 13, 2022
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7NF7
| Ovine rBAT ectodomain homodimer, asymmetric unit | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lee, Y, Kuehlbrandt, W. | Deposit date: | 2021-02-05 | Release date: | 2022-01-19 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria. Nat Commun, 13, 2022
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8GW6
| AtSLAC1 6D mutant in closed state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | Authors: | Lee, Y, Lee, S. | Deposit date: | 2022-09-16 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GW7
| AtSLAC1 6D mutant in open state | Descriptor: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | Authors: | Lee, Y, Lee, S. | Deposit date: | 2022-09-16 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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7NF6
| Ovine b0,+AT-rBAT heterodimer | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lee, Y, Kuehlbrandt, W. | Deposit date: | 2021-02-05 | Release date: | 2022-01-19 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Ca 2+ -mediated higher-order assembly of heterodimers in amino acid transport system b 0,+ biogenesis and cystinuria. Nat Commun, 13, 2022
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1FBT
| THE BISPHOSPHATASE DOMAIN OF THE BIFUNCTIONAL RAT LIVER 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | FRUCTOSE-2,6-BISPHOSPHATASE, PHOSPHATE ION | Authors: | Lee, Y.-H, Ogata, C, Pflugrath, J.W, Levitt, D.G, Sarma, R, Banaszak, L.J, Pilkis, S.J. | Deposit date: | 1996-03-08 | Release date: | 1997-07-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the rat liver fructose-2,6-bisphosphatase based on selenomethionine multiwavelength anomalous dispersion phases. Biochemistry, 35, 1996
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5TSP
| Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Sialidase | Authors: | Lee, Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Kang, J.Y, Jin, M.S, Ryu, Y.B, Park, K.H, Eom, S.H. | Deposit date: | 2016-10-31 | Release date: | 2017-03-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid Biochem. Biophys. Res. Commun., 486, 2017
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4XVM
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4XVI
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5BZ6
| Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-06-11 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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