6TKO
Phosphorylated turkey beta1 adrenoceptor with bound agonist formoterol coupled to arrestin-2 in lipid nanodisc.
Summary for 6TKO
Entry DOI | 10.2210/pdb6tko/pdb |
Related | 6IBL |
EMDB information | 10515 |
Descriptor | Beta-1 adrenergic receptor, Beta-arrestin-1, Fab30 heavy chain, ... (5 entities in total) |
Functional Keywords | gpcr, arrestin, complex, nanodisc, signaling protein |
Biological source | Meleagris gallopavo (Wild turkey) More |
Total number of polymer chains | 4 |
Total formula weight | 133588.55 |
Authors | Lee, Y.,Tate, C.G. (deposition date: 2019-11-28, release date: 2020-06-17, Last modification date: 2020-08-12) |
Primary citation | Lee, Y.,Warne, T.,Nehme, R.,Pandey, S.,Dwivedi-Agnihotri, H.,Chaturvedi, M.,Edwards, P.C.,Garcia-Nafria, J.,Leslie, A.G.W.,Shukla, A.K.,Tate, C.G. Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor. Nature, 583:862-866, 2020 Cited by PubMed: 32555462DOI: 10.1038/s41586-020-2419-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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